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Effect of Health Insurance on Hepatitis C Sustained Virologic Response Rates to Sofosbuvir-Based Treatment Regimens in a South Florida Community Hospital
- Source :
- Journal of the International Association of Providers of AIDS Care, Journal of the International Association of Providers of AIDS Care, Vol 18 (2019)
- Publication Year :
- 2019
- Publisher :
- SAGE Publications, 2019.
-
Abstract
- The high cost of direct-acting antiviral–based regimens raises concerns about the outcome of treatment in uninsured patients with chronic hepatitis C virus (HCV) infection. This study assessed the relationship between health insurance status and sustained virologic response (SVR) rates in a community hospital in South Florida. Sofosbuvir-based therapy was initiated in 82 patients, of which 73% were uninsured and 28 (34%) were HIV coinfection. The overall SVR rate for those tested was 98%. The SVR rates were similar between HCV mono- and HCV/HIV coinfected patients (96% versus 100%, P = .204). Uninsured patients, with access to patient assistance programs, had comparable SVR rates to insured patients (100% versus 95%, P = .131). However, there was a trend toward a higher rate of loss to follow-up in uninsured compared to insured patients (25% versus 9%, P = .116). Strategies specific to adherence to treatment for uninsured patients are needed to reduce rates of loss to follow-up.
- Subjects :
- Male
sofosbuvir-based regimens
Sustained Virologic Response
Sofosbuvir
Human immunodeficiency virus (HIV)
HIV Infections
Hospitals, Community
Hepacivirus
lcsh:RC870-923
medicine.disease_cause
Insurance Coverage
0302 clinical medicine
Medicine
030212 general & internal medicine
Medically Uninsured
Treatment regimen
virus diseases
Hepatitis C
Middle Aged
Community hospital
Treatment Outcome
Infectious Diseases
Florida
Original Article
Drug Therapy, Combination
Female
030211 gastroenterology & hepatology
medicine.drug
medicine.medical_specialty
SVR
Immunology
Dermatology
Antiviral Agents
03 medical and health sciences
Internal medicine
Health insurance
chronic hepatitis C
Humans
Retrospective Studies
Insurance, Health
business.industry
HIV
insurance status
Hepatitis C, Chronic
lcsh:Diseases of the genitourinary system. Urology
medicine.disease
digestive system diseases
Virologic response
Patient assistance
business
Subjects
Details
- ISSN :
- 23259582
- Volume :
- 18
- Database :
- OpenAIRE
- Journal :
- Journal of the International Association of Providers of AIDS Care (JIAPAC)
- Accession number :
- edsair.doi.dedup.....6317d1d48be825a28c4ee890b20de11d