Familial Lund frontotemporal dementia caused by C9ORF72 hexanucleotide expansion

Authors :: Elisabet Englund
Elisa Majounie
Bryan J. Traynor
Jonathan D. Rohrer
John Hardy
Alan E. Renton
Ulla Passant
Lars Gustafson
Kin Y. Mok
Source :: Neurobiology of Aging. 33:1850.e13-1850.e16
Publication Year :: 2012
Publisher :: Elsevier BV, 2012.
Abstract: Frontotemporal dementia (FTD) as an important clinical entity was rediscovered in Lund and Manchester in the early 1990s. Here we show that the large Lund pedigree with behavioral variant of frontotemporal dementia previously described with this disorder has an expansion in the recently described C9ORF72 locus on chromosome 9.

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