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CatecholamineāOuabain Interaction on the Isolated Perfused Rat Heart
- Source :
- Canadian Journal of Physiology and Pharmacology. 53:150-154
- Publication Year :
- 1975
- Publisher :
- Canadian Science Publishing, 1975.
-
Abstract
- The effect of catecholamine-depleting pretreatments, reserpine, and 6-hydroxydopamine (6-OH-DA) on left ventricular pressure (LVP) and the inotropic response to graded doses of ouabain (up to 300 Ī¼g/0.05 ml) was studied in isolated perfused rat and guinea-pig hearts. In rats, reserpine and 6-OH-DA depleted myocardial catecholamine content (p
- Subjects :
- Inotrope
endocrine system
medicine.medical_specialty
Reserpine
Physiology
Guinea Pigs
In Vitro Techniques
Ouabain
Hydroxydopamines
Norepinephrine
Catecholamines
Physiology (medical)
Internal medicine
medicine
Animals
Pharmacology
business.industry
Myocardium
Heart
General Medicine
Rat heart
Electric Stimulation
Stimulation, Chemical
Rats
Endocrinology
Catecholamine
Ventricular pressure
business
medicine.drug
Subjects
Details
- ISSN :
- 12057541 and 00084212
- Volume :
- 53
- Database :
- OpenAIRE
- Journal :
- Canadian Journal of Physiology and Pharmacology
- Accession number :
- edsair.doi.dedup.....625f92f3b4f1e8aafccbd2d25412c1a0
- Full Text :
- https://doi.org/10.1139/y75-021