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MRI Evidence of Neuropathic Changes in Former College Football Players
- Source :
- Clinical Journal of Sport Medicine. 28:100-105
- Publication Year :
- 2018
- Publisher :
- Ovid Technologies (Wolters Kluwer Health), 2018.
-
Abstract
- OBJECTIVE To examine effects of participating in collegiate football on neural health several years after retirement. We hypothesized that relative cortical thinning and loss of white matter integrity would be observed in former players. DESIGN Former NCAA Division I football players were compared with demographically similar track-and-field athletes with regard to cortical thickness and white matter integrity. SETTING Participants participated in MRI scans at the Center for Imaging Research at the University of Cincinnati. PARTICIPANTS Eleven former football players and 10 demographically similar track-and-field athletes. MAIN OUTCOME MEASURES Normalized cortical thickness was compared between groups using 2-tailed Student t test. As a secondary analysis, Spearman correlation coefficient was calculated between cortical thickness and number of concussions. Fractional anisotropy for regions-of-interest placed in frontal white matter tracts and internal capsule were compared between groups using 2-tailed Student t test. RESULTS Football players showed significantly lower cortical thickness within portions of both the frontal and temporal cortex. Affected frontal regions included left frontal pole and right superior frontal gyrus. Affected temporal regions included portions of the superior temporal gyrus, left inferior temporal gyrus, and right middle and superior temporal gyri. Cortical thickness inversely correlated with number of reported concussions over most of these regions. In addition, fractional anisotropy was lower in the right internal capsule of former football players, relative to controls. CONCLUSIONS These findings suggest that at least some consequences of high-level collegiate football play persist even after the cessation of regular head blows. Longer-term studies are warranted to examine potential cognitive and functional implications of sustained cortical atrophy.
- Subjects :
- Adult
medicine.medical_specialty
Internal capsule
Football
Prefrontal Cortex
Physical Therapy, Sports Therapy and Rehabilitation
Temporal lobe
White matter
Young Adult
03 medical and health sciences
Superior temporal gyrus
0302 clinical medicine
Physical medicine and rehabilitation
Fractional anisotropy
medicine
Humans
Orthopedics and Sports Medicine
Prefrontal cortex
Brain Concussion
Temporal cortex
business.industry
030229 sport sciences
Magnetic Resonance Imaging
White Matter
Temporal Lobe
Diffusion Tensor Imaging
medicine.anatomical_structure
Athletes
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 1050642X
- Volume :
- 28
- Database :
- OpenAIRE
- Journal :
- Clinical Journal of Sport Medicine
- Accession number :
- edsair.doi.dedup.....62346af7be4d450f2d09738ed214f36a