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Role of the left coronary artery geometry configuration in atherosusceptibility: CFD simulations considering sPTT model for blood

Authors :
E. Miranda
Catarina F. Castro
Luísa Costa Sousa
S.I.S. Pinto
Carlos Alberto Conceição António
Source :
Computer Methods in Biomechanics and Biomedical Engineering. 24:1488-1503
Publication Year :
2021
Publisher :
Informa UK Limited, 2021.

Abstract

The achievement of clinically viable methodologies to simulate the hemodynamics in patient-specific coronary arteries is still a major challenge. Therefore, the novelty of this work is attained by the introduction of the viscoelastic property of blood in the numerical simulations, to study the role of the left coronary artery (LCA) geometry configuration in the atherosusceptibility. Apparently healthy patients were used and four different methodologies were tested. The methodology giving the most accurate results at the same time of having the lowest computational time is the one considering the viscoelastic property of blood and computational fluid dynamics. A Pearson correlation analysis was used to highlight relationships between geometric configuration and hemodynamic descriptors based on the simulated wall shear stress (WSS). The left main stem (LMS) has the greatest atherosusceptibility followed by the left anterior descending artery (LAD) since the relative residence time (RRT) average values are 3.81 and 3.70 Pa

Details

ISSN :
14768259 and 10255842
Volume :
24
Database :
OpenAIRE
Journal :
Computer Methods in Biomechanics and Biomedical Engineering
Accession number :
edsair.doi.dedup.....61c4eb7221926b42bec6cf1ead29503a
Full Text :
https://doi.org/10.1080/10255842.2021.1894555