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Spreading of canine parvovirus type 2c mutants of Asian origin in southern Italy
- Source :
- Transboundary and Emerging Diseases
- Publication Year :
- 2019
- Publisher :
- Hindawi Limited, 2019.
-
Abstract
- Canine parvovirus type 2 (CPV‐2) emerged as dog pathogen in the late 1970s, causing severe and often fatal epizootics of gastroenteritis in the canine population worldwide. Although to date CPV‐2 is circulating in all continents, most of the current studies have analysed the amino acid changes accounted in the VP2 gene sequence, with limited information on virus introductions from other countries. The aim of this study was to analyse the genetic features of CPV‐2c strains currently spreading in Italy. Swabs and tissue samples were collected from dogs suspected of CPV infection. The nearly complete genome sequence from the CPV‐positive samples was obtained. The co‐circulation of two different but related CPV‐2c strains, with amino acid changes characteristic of CPV strains of Asian origin (NS1: 60V, 544F, 545F, 630P – NS2: 60V, 151N, 152V ‐ VP2: 5A/G, 267Y, 297A, 324I, 370R), were observed. The phylogenetic analyses inferred from the NS1 and VP2 gene sequences confirmed the relationship with Asian CPV‐2c strains. This study reports the spread of novel CPV‐2c mutants in Italy and supports further studies to evaluate the coexistence of genetically divergent CPV strains in the same geographical environment.
- Subjects :
- dogs
Asia
sequence analysis
Parvovirus, Canine
040301 veterinary sciences
Sequence analysis
animal diseases
viruses
Mutant
Population
Polymerase Chain Reaction
Virus
molecular characterization
Parvoviridae Infections
0403 veterinary science
03 medical and health sciences
Animals
Dog Diseases
education
Pathogen
Phylogeny
030304 developmental biology
Whole genome sequencing
0303 health sciences
education.field_of_study
General Veterinary
General Immunology and Microbiology
biology
Phylogenetic tree
canine parvovirus
Canine parvovirus
Original Articles
04 agricultural and veterinary sciences
General Medicine
biology.organism_classification
Virology
Italy
Mutation
carnivore protoparvovirus
Original Article
Subjects
Details
- ISSN :
- 18651682 and 18651674
- Volume :
- 66
- Database :
- OpenAIRE
- Journal :
- Transboundary and Emerging Diseases
- Accession number :
- edsair.doi.dedup.....6189069f0086a0662e9bff0b9153ec06