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Poor Antibody Response After Two Doses of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine in Transplant Recipients

Authors :
A. Mazzola
Eve Todesco
Fanny Hazan
Dominique Thabut
Benoit Barrou
Anne-Geneviève Marcelin
Filomena Conti
Stéphane Marot
Cathia Soulié
Sheida Varnous
Sarah J. Drouin
Source :
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Publication Year :
2021
Publisher :
Oxford University Press (OUP), 2021.

Abstract

A low anti-spike antibody response of 28.6% was observed 28 days after BNT162b2 vaccine second dose among 133 solid organ transplant recipients without previous coronavirus disease 2019 (COVID-19). No serious adverse events were recorded. Four severe COVID-19 cases were reported between or after the 2 doses. Our data suggest to change the vaccine strategy.

Details

ISSN :
15376591 and 10584838
Volume :
74
Database :
OpenAIRE
Journal :
Clinical Infectious Diseases
Accession number :
edsair.doi.dedup.....61573c8739f1f5cc9456066a0933cf9c