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Association between Hypomagnesemia, COVID-19, Respiratory Tract and Lung Disease
- Source :
- The Open Respiratory Medicine Journal
- Publication Year :
- 2021
- Publisher :
- Bentham Science Publishers Ltd., 2021.
-
Abstract
- The complexity of COVID-19 is also related to the multiple molecular pathways triggered by SARS-CoV-2, which is able to cause type I pneumocyte death, trigger intravascular coagulation, interfere with the renin-angiotensin system, dysregulate iron metabolism, ending with the insurgence of a cytokine storm which may lead to death. Old adults with obesity, hypertension, and diabetes are among the high-risk category groups more prone to SARS-CoV-2 infection. Magnesium has been reported to play a major role both in physiology and in pathology, particularly in elderly people, regulating cytotoxic functions of natural killer (NK) cells and CD8+ T lymphocytes. In spite of the absence of controlled trials, the possibility of magnesium supplementation for supportive treatment in patients with COVID-19 should be encouraged. This could be useful in all phases of the COVID-19 disease.
- Subjects :
- Pulmonary and Respiratory Medicine
Effects
business.industry
COVID-19
Disease
medicine.disease
Article
Magnesium deficiency
Hypomagnesemia
medicine.anatomical_structure
Magnesium deficiency (medicine)
Diabetes mellitus
Immunology
medicine
Cytotoxic T cell
Magnesium
Obesity
Cytokine storm
business
Lung diseases
CD8
Respiratory tract
Subjects
Details
- ISSN :
- 18743064
- Volume :
- 15
- Database :
- OpenAIRE
- Journal :
- The Open Respiratory Medicine Journal
- Accession number :
- edsair.doi.dedup.....612b3e00c95c75fab527ea443465b142