Back to Search Start Over

Progesterone rise on the day of human chorionic gonadotropin administration impairs pregnancy outcome in day 3 single-embryo transfer, while has no effect on day 5 single blastocyst transfer

Authors :
Cristina Pozzobon
Claire Bourgain
Herman Tournaye
Evangelos G. Papanikolaou
André Van Steirteghem
Paul Devroey
Efstratios M. Kolibianakis
Parikshit Tank
Department of Embryology and Genetics
Pathological Anatomy
Reproductive immunology and implantation
Centre for Reproductive Medicine - Gynaecology
Publication Year :
2009
Publisher :
Elsevier Inc., 2009.

Abstract

Four hundred eighty-two patients undergoing single ET with GnRH-antagonist/recFSH protocol were analyzed. The incidence of premature luteinization (P above 1.5 ng/mL on the day of hCG administration) was 18.2%. Even modest rises of P in the follicular phase have detrimental effect on the implantation potential of a good-quality cleavage stage embryo. On the contrary, premature luteinization in the blastocyst subgroup had no effect on the pregnancy outcome.

Details

Language :
English
Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....611e071232da384d54483b39e7571723