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Effects of low-dose dopamine on urine output in normotensive very low birth weight neonates
- Source :
- Journal of perinatology : official journal of the California Perinatal Association. 33(8)
- Publication Year :
- 2012
-
Abstract
- To determine the effects of low-dose dopamine on urine output (UOP) in very low birth weight premature neonates.Retrospective cohort study of all low-dose (3-5 μg kg(-1) per min) dopamine infusions24-h duration in neonates 1500 g and 32 weeks gestation from August 2009 through September 2011. Linear regression was used to estimate the impact of covariates on UOP.We identified 91 episodes of low-dose dopamine use in 65 neonates. Increased UOP occurred in 64% of episodes. Low-dose dopamine use was associated with a 0.6 ml kg(-1) h(-1) increase in UOP (P0.001) and a 1.3 ml kg(-1)h(-1) increase when baseline UOP was1.5 ml kg(-1) h(-1) (P0.001). The improvement remained statistically significant after controlling for medications (diuretics and hydrocortisone) and fluid intake.Low-dose dopamine use was associated with increased UOP in very low birth weight neonates.
- Subjects :
- Male
medicine.medical_specialty
media_common.quotation_subject
Dopamine
Urination
Urine
Kidney
Article
Internal medicine
Medicine
Humans
Infant, Very Low Birth Weight
Urine output
media_common
Retrospective Studies
business.industry
Low dose
Infant, Newborn
Obstetrics and Gynecology
Low birth weight
Endocrinology
medicine.anatomical_structure
Renal physiology
Pediatrics, Perinatology and Child Health
Female
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 14765543
- Volume :
- 33
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Journal of perinatology : official journal of the California Perinatal Association
- Accession number :
- edsair.doi.dedup.....611b3cfb3462580d4f5d0d5e1d05bd63