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Mobilisation strategies for normal and malignant cells
- Source :
- Pathology. 43:547-565
- Publication Year :
- 2011
- Publisher :
- Elsevier BV, 2011.
-
Abstract
- This review evaluates the latest information on the mobilisation of haemopoietic stem cells for transplantation, with the focus on what is the current best practice and how new understanding of the bone marrow stem cell niche provides new insights into optimising mobilisation regimens. The review then looks at the mobilisation of mesenchymal stromal cells, immune cells as well as malignant cells and what clinical implications there are.
- Subjects :
- Transplantation Conditioning
business.industry
Mesenchymal stem cell
Hematopoietic Stem Cell Transplantation
Bone Marrow Stem Cell
Mesenchymal Stem Cells
Stem cell factor
Hematopoietic Stem Cells
medicine.disease
Hematopoietic Stem Cell Mobilization
Pathology and Forensic Medicine
Granulocyte colony-stimulating factor
Transplantation
Graft-versus-host disease
Granulocyte macrophage colony-stimulating factor
Models, Animal
Immunology
medicine
Cancer research
Animals
Humans
Stem cell
business
medicine.drug
Subjects
Details
- ISSN :
- 00313025
- Volume :
- 43
- Database :
- OpenAIRE
- Journal :
- Pathology
- Accession number :
- edsair.doi.dedup.....610529aff632ce337a1d05d9993cdf86