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Is capillary ketone determination useful in clinical practice? In which circumstances?
- Source :
- Diabetes & Metabolism. 31:299-303
- Publication Year :
- 2005
- Publisher :
- Elsevier BV, 2005.
-
Abstract
- Summary A new method is now available to measure capillary levels of 3hydroxybutyrate (3HB), one of the three ketone bodies. It is a quantitative and enzymatic test that uses the same equipment as for home capillary blood glucose determination but with specific strips. In comparison to urine ketone test, there is no false negative or false positive results, it is highly correlate to standard automate assays and patients find it more acceptable. Clinical implementations of this new test begin to be reported. Some studies showed an advantage of ketonemia versus ketonuria measurement to detect and to treat diabetic ketoacidosis in the emergency room. In diabetic patients treated with continuous subcutaneous insulin infusion, ketonemia seems to be more relevant to detect lack of insulin. In the current care of patient with type 1 diabetes and especially in children blood ketone test is more effective than urine ketone test to prevent hospitalisation during sick days. For other situations such as diabetic pregnancy or type 2 diabetes, more data are needed to determine if capillary measurement of 3HB is really useful. This new test is easier and less unpleasant than doing urinary test but it is still far more expensive. Further clinical studies are needed to define whether self 3HB monitoring should substitute urinary test in outpatient care.
- Subjects :
- medicine.medical_specialty
Diabetic ketoacidosis
Endocrinology, Diabetes and Metabolism
medicine.medical_treatment
Pregnancy in Diabetics
Ketone Bodies
Type 2 diabetes
Diabetic Ketoacidosis
Endocrinology
Pregnancy
Diabetes mellitus
Internal Medicine
medicine
Humans
Child
Intensive care medicine
Type 1 diabetes
business.industry
Insulin
Reproducibility of Results
General Medicine
medicine.disease
Capillaries
Ketoacidosis
Surgery
Diabetes Mellitus, Type 1
Ketone bodies
Ketonuria
Female
business
Biomarkers
Subjects
Details
- ISSN :
- 12623636
- Volume :
- 31
- Database :
- OpenAIRE
- Journal :
- Diabetes & Metabolism
- Accession number :
- edsair.doi.dedup.....60ce61eb01ba3bcdf838aea48441485c