Reactive angioendotheliomatosis and sarcoidosis

Angioendotheliomatosis is an uncommon condition that manifests with both cutaneous and systemic clinical signs and symptoms. It is characterized histologically by the proliferation of endothelial cells within vascular lumina resulting in the obliteration of the involved vessels secondary to intravascular thrombi. Cases have been classically divided into the benign or reactive variants and a malignant variant. The reactive variant is considerably more rare and has mainly been described in patients with systemic infections including subacute bacterial endocarditis. In this report we present a case of reactive angioendotheliomatosis in a patient with sarcoidosis.