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Reactive oxygen species-induced alterations in H19-Igf2 methylation patterns, seminal plasma metabolites, and semen quality
- Source :
- Journal of Assisted Reproduction and Genetics. 36:241-253
- Publication Year :
- 2018
- Publisher :
- Springer Science and Business Media LLC, 2018.
-
Abstract
- PURPOSE: This study was conducted in order to investigate the effects of reactive oxygen species (ROS) levels on the seminal plasma (SP) metabolite milieu and sperm dysfunction. METHODS: Semen specimens of 151 normozoospermic men were analyzed for ROS by chemiluminescence and classified according to seminal ROS levels [in relative light units (RLU)/s/10(6) sperm]: group 1 (n = 39): low (ROS
- Subjects :
- Male
0301 basic medicine
Reproductive Techniques, Assisted
Metabolite
Semen
DNA Fragmentation
medicine.disease_cause
Antioxidants
Male infertility
Andrology
03 medical and health sciences
Semen quality
chemistry.chemical_compound
0302 clinical medicine
Insulin-Like Growth Factor II
Genetics
medicine
Humans
Infertility, Male
Genetics (clinical)
Sperm motility
030219 obstetrics & reproductive medicine
Sperm Count
business.industry
Obstetrics and Gynecology
General Medicine
Methylation
DNA Methylation
medicine.disease
Spermatozoa
Sperm
Semen Analysis
Oxidative Stress
Reproductive Physiology and Disease
030104 developmental biology
Reproductive Medicine
chemistry
Sperm Motility
RNA, Long Noncoding
Reactive Oxygen Species
business
Oxidative stress
Developmental Biology
Subjects
Details
- ISSN :
- 15737330 and 10580468
- Volume :
- 36
- Database :
- OpenAIRE
- Journal :
- Journal of Assisted Reproduction and Genetics
- Accession number :
- edsair.doi.dedup.....60725e8c3bc633e90d5bb2ccb4ee9101
- Full Text :
- https://doi.org/10.1007/s10815-018-1350-y