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Reactive oxygen species-induced alterations in H19-Igf2 methylation patterns, seminal plasma metabolites, and semen quality

Authors :
Mahsa Darbandi
Hamid Reza Khorram Khorshid
Ashok Agarwal
Pallav Sengupta
Sara Darbandi
Saradha Baskaran
Fatemeh Nobakht
Niknam Lakpour
Mohammad Reza Sadeghi
Sandro C. Esteves
Mehdi Hedayati
Kambiz Gilany
Mohammad Mehdi Akhondi
Sulagna Dutta
Source :
Journal of Assisted Reproduction and Genetics. 36:241-253
Publication Year :
2018
Publisher :
Springer Science and Business Media LLC, 2018.

Abstract

PURPOSE: This study was conducted in order to investigate the effects of reactive oxygen species (ROS) levels on the seminal plasma (SP) metabolite milieu and sperm dysfunction. METHODS: Semen specimens of 151 normozoospermic men were analyzed for ROS by chemiluminescence and classified according to seminal ROS levels [in relative light units (RLU)/s/10(6) sperm]: group 1 (n = 39): low (ROS

Details

ISSN :
15737330 and 10580468
Volume :
36
Database :
OpenAIRE
Journal :
Journal of Assisted Reproduction and Genetics
Accession number :
edsair.doi.dedup.....60725e8c3bc633e90d5bb2ccb4ee9101
Full Text :
https://doi.org/10.1007/s10815-018-1350-y