Intramuscular hyaluronic acid expression following repetitive power training induced nonfunctional overreaching

Hyaluronic acid (HA) contributes to extracellular matrix viscosity and fiber regeneration. HA role in resistance training (RT) performance adaptations is unclear. RT men performed power training (nonfunctional overreaching (NFOR) or normal training (CG)) over 7.5 days. Post RT, the CG improved power while NFOR did not with HA content decreasing 34.5% in NFOR with no change in CG. HA is critical for muscular recovery; decreased HA may contribute to impaired power adaptations with NFOR RT. Novelty: Nonfunctional over-reaching decreases muscular hyaluronic acid.