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Effects of acupuncture on anthropometric and serum metabolic parameters in premenopausal overweight and obese women: a randomized, patient- and assessor-blind, sham-controlled clinical trial
- Source :
- Acupuncture in Medicine. 39:30-40
- Publication Year :
- 2020
- Publisher :
- SAGE Publications, 2020.
-
Abstract
- Objective: The aim of this study was to examine the effect of acupuncture on obesity-related parameters with regard to metabolomics. Methods: This two-arm parallel, patient- and assessor-blind, sham-controlled randomized clinical trial included 120 obese participants. Participants were randomized into two groups. The treatment group received a combined intervention of manual acupuncture (MA) plus electroacupuncture (EA), while the control group received a combination of sham acupuncture interventions consisting of sham MA plus sham EA for 6 weeks. The serum lipid levels were measured as the primary outcome measure and anthropometric parameters and serum metabolic profiles including amino acids and carnitines were measured as secondary outcome measures. Results: The serum lipid levels and anthropometric measurements did not significantly differ between groups, while body weight, body mass index (BMI), and waist circumference were improved within each group and the level of high-density lipoprotein cholesterol increased over time in the treatment group. There were no significant differences in amino acid levels between groups, while certain carnitine (C2, C4, C6, and l-carnitine) levels were significantly increased ( p Conclusion: In summary, 6 weeks of acupuncture treatment did not affect anthropometric and serum metabolic parameters, with the exception of certain carnitines, when compared to sham acupuncture. The observation of increased carnitine levels in the acupuncture group could result in potential long-term benefits to obese individuals. Additional studies are needed to investigate the long-term effects of acupuncture on lipid metabolism and the underlying mechanism of action. Trial registration number: This study is registered at ClinicalTrials.gov (NCT02066090).
- Subjects :
- Adult
medicine.medical_specialty
Acupuncture Therapy
Overweight
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
Carnitine
medicine
Acupuncture
Humans
Obesity
Prospective Studies
Amino Acids
Anthropometry
business.industry
General Medicine
Middle Aged
medicine.disease
030205 complementary & alternative medicine
Clinical trial
Electroacupuncture
Treatment Outcome
Premenopause
Complementary and alternative medicine
030220 oncology & carcinogenesis
Physical therapy
Female
Neurology (clinical)
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 17599873 and 09645284
- Volume :
- 39
- Database :
- OpenAIRE
- Journal :
- Acupuncture in Medicine
- Accession number :
- edsair.doi.dedup.....601353ad14f5679e75e418d34fbbf3c0