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Worsening Knee Osteoarthritis Features on Magnetic Resonance Imaging 1 to 5 Years After Anterior Cruciate Ligament Reconstruction
- Source :
- The American Journal of Sports Medicine. 46:2873-2883
- Publication Year :
- 2018
- Publisher :
- SAGE Publications, 2018.
-
Abstract
- Background: An anterior cruciate ligament (ACL) injury is a well-established risk factor for the long-term development of radiographic osteoarthritis (OA). However, little is known about the early degenerative changes (ie, Purpose: To describe early degenerative changes between 1 and 5 years after ACL reconstruction (ACLR) on magnetic resonance imaging (MRI) and explore participant characteristics associated with these changes. Study Design: Case-control study; Level of evidence, 3. Methods: Seventy-eight participants (48 men; median age, 32 years; median body mass index [BMI], 26 kg/m2) underwent 3.0-T MRI at 1 and 5 years after primary hamstring autograft ACLR. Early tibiofemoral and patellofemoral OA features were assessed with the MRI Osteoarthritis Knee Score. The primary outcome was worsening (ie, incident or progressive) cartilage defects, bone marrow lesions (BMLs), osteophytes, and meniscal lesions. Logistic regression with generalized estimating equations evaluated participant characteristics associated with worsening features. Results: Worsening of cartilage defects in any compartment occurred in 40 (51%) participants. Specifically, worsening in the patellofemoral and medial and lateral tibiofemoral compartments was present in 34 (44%), 8 (10%), and 10 (13%) participants, respectively. Worsening patellofemoral and medial and lateral tibiofemoral BMLs (14 [18%], 5 [6%], and 10 [13%], respectively) and osteophytes (7 [9%], 8 [10%], and 6 [8%], respectively) were less prevalent, while 17 (22%) displayed deteriorating meniscal lesions. Worsening of at least 1 MRI-detected OA feature, in either the patellofemoral or tibiofemoral compartment, occurred in 53 (68%) participants. Radiographic OA in any compartment was evident in 5 (6%) and 16 (21%) participants at 1 and 5 years, respectively. A high BMI (>25 kg/m2) was consistently associated with elevated odds (between 2- and 5-fold) of worsening patellofemoral and tibiofemoral OA features. Conclusion: High rates of degenerative changes occur in the first 5 years after ACLR, particularly the development and progression of patellofemoral cartilage defects. Older patients with a higher BMI may be at particular risk and should be educated about this risk.
- Subjects :
- Adult
Male
medicine.medical_specialty
Time Factors
Anterior cruciate ligament reconstruction
Radiography
medicine.medical_treatment
Anterior cruciate ligament
Physical Therapy, Sports Therapy and Rehabilitation
Osteoarthritis
Article
Young Adult
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Humans
Medicine
Orthopedics and Sports Medicine
030203 arthritis & rheumatology
Anterior Cruciate Ligament Reconstruction
medicine.diagnostic_test
business.industry
Anterior Cruciate Ligament Injuries
Cartilage
Magnetic resonance imaging
030229 sport sciences
Middle Aged
Osteoarthritis, Knee
medicine.disease
Magnetic Resonance Imaging
medicine.anatomical_structure
Case-Control Studies
Disease Progression
Female
Median body
Radiology
business
Hamstring
Subjects
Details
- ISSN :
- 15523365 and 03635465
- Volume :
- 46
- Database :
- OpenAIRE
- Journal :
- The American Journal of Sports Medicine
- Accession number :
- edsair.doi.dedup.....5ff055d4d7ccba0b153a621416e3c8d7