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Soluble guanylate cyclase isoenzymes: The expression of α1, α2, β1, and β2 subunits in the benign and malignant breast tumors
- Source :
- Journal of cellular physiology. 235(2)
- Publication Year :
- 2018
-
Abstract
- Soluble guanylate cyclase (sGC) encompasses α and β subunits. This study examined the expression of α1, α2, β1, and β2 subunits in the malignant and benign breast tumors using the Western blot analysis. Both benign and malignant tumors showed a significantly higher expression of the α1 subunit in comparison with normal tissues (p
- Subjects :
- inorganic chemicals
0301 basic medicine
Adult
Physiology
Protein subunit
Clinical Biochemistry
Breast Neoplasms
Isozyme
03 medical and health sciences
0302 clinical medicine
Breast cancer
Soluble Guanylyl Cyclase
Downregulation and upregulation
Tumor stage
medicine
Biomarkers, Tumor
Humans
heterocyclic compounds
Aged
chemistry.chemical_classification
Carcinoma, Ductal, Breast
Cell Biology
Middle Aged
medicine.disease
Benign breast tumors
Isoenzymes
030104 developmental biology
Enzyme
chemistry
Fibroadenoma
030220 oncology & carcinogenesis
cardiovascular system
Cancer research
Female
Guanylate cyclase
Subjects
Details
- ISSN :
- 10974652
- Volume :
- 235
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of cellular physiology
- Accession number :
- edsair.doi.dedup.....5fb7eec4ccf044dd7016a0f0b023b325