Successful treatment of hereditary factor VII deficiency presented for the first time with epistaxis in pregnancy: a case report

Objective. To present a rare case with factor VII deficiency (FVIID) that first diagnosed during pregnancy, and to disscuss the ante-, peri- and postpartum management.Study Design. A case report and review of the literature.Results. FVIID was diagnosed for the first time in a 23-year-old pregnant woman at the 24th week of gestation due to complaint of intermittent epistaxis. She was succesfully treated by ante-, peripartum and postpartum replacement of recombinant FVII (rFVII). She was uneventfully discharged on the 3rd postoperative day and refered to hematology department for further follow-up.Conclusion. FVIID, a rare cause of ante- and postpartum hemorrhagies that may differently present by other hemorrhagies (i.e.: epistaxis), can be optimally managed with replacement of rFVII.