Quinoline-3-carboxamides such as tasquinimod are not specific inhibitors of S100A9

TO THE EDITOR: We read with great interest the article by Yoshioka et al published recently in Blood Advances and suggesting a critical role for S100A9 and neutrophils in granuloma formation.[1][1] The authors used tasquinimod to block S100A9 activity and referred to it as an S100A9 inhibitor.