Cladribine as a Potential Object of Nucleoside Transporter-Based Drug Interactions

Authors :: Robert Hermann
Peter Krajcsi
Markus Fluck
Annick Seithel-Keuth
Afrim Bytyqi
Andrew Galazka
Alain Munafo
Source :: Clinical Pharmacokinetics. 61:167-187
Publication Year :: 2021
Publisher :: Springer Science and Business Media LLC, 2021.
Abstract: Cladribine is a nucleoside analog that is phosphorylated in its target cells (B and T-lymphocytes) to its active triphosphate form (2-chlorodeoxyadenosine triphosphate). Cladribine tablets 10 mg (Mavenclad

Subjects :: Equilibrative Nucleoside Transporter 1
Pharmacology
ATP Binding Cassette Transporter, Subfamily G, Member 2
Cladribine
Humans
Membrane Transport Proteins
ATP-Binding Cassette Transporters
Drug Interactions
Pharmacology (medical)
Nucleoside Transport Proteins
Neoplasm Proteins

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