Impact of overweight/obesity on clinical outcomes after reduction for intussusception in children

Childhood obesity is a worsening epidemic. Little is known about the impact of overweight and obesity (OV–OB) on clinical outcomes after reduction for intussusception in children. The aim of this study was to compare clinical outcomes after primarily air enema reduction for intussusception in grouped OV–OB (body mass index-for-age percentile ≥ 85) pediatric patients compared with no OV–OB patients. A retrospective study of 564 children who had undergone intussusception reduction via pneumatic reduction (PR) from April 2018 to January 2020 was conducted with assessments of demographic data, clinical symptoms, pre-reduction examination, and reduction results. One-to-one propensity score matching (PSM) was performed to compare clinical outcomes between patients with and without OV–OB, and the risk factors affecting recurrence and surgical reduction were analyzed in the PSM population. Of the 564 patients, 132 cases (23.4%) were OV–OB (overweight: 95 cases; obesity: 37 cases). In the propensity-matched analysis, the OV–OB group showed a significant increase in surgical reduction (10.2% versus 0.9%, P = 0.005) and recurrence (47.2% versus 10.2%, P