Back to Search
Start Over
Multidrug Resistance-Like Genes of Arabidopsis Required for Auxin Transport and Auxin-Mediated Development
- Source :
- The Plant Cell. 13:2441
- Publication Year :
- 2001
- Publisher :
- JSTOR, 2001.
-
Abstract
- Arabidopsis possesses several genes related to the multidrug resistance (MDR) genes of animals, one of which, AtMDR1, was shown to be induced by the hormone auxin. Plants having mutations in AtMDR1 or its closest relative, AtPGP1, were isolated by a reverse genetic strategy. Auxin transport activity was greatly impaired in atmdr1 and atmdr1 atpgp1 double mutant plants. Epinastic cotyledons and reduced apical dominance were mutant phenotypes consistent with the disrupted basipetal flow of auxin. The auxin transport inhibitor 1-naphthylphthalamic acid was shown to bind tightly and specifically to AtMDR1 and AtPGP1 proteins. The results indicate that these two MDR-like genes of Arabidopsis encode 1-naphthylphthalamic acid binding proteins that are required for normal auxin distribution and auxin-mediated development.
- Subjects :
- Auxin influx
Auxin efflux
Molecular Sequence Data
Arabidopsis
Saccharomyces cerevisiae
Plant Science
Biology
Plant Roots
Auxin
heterocyclic compounds
Cloning, Molecular
PIN proteins
DNA Primers
chemistry.chemical_classification
Genetics
Base Sequence
Indoleacetic Acids
Reverse Transcriptase Polymerase Chain Reaction
Brassica napus
Genetic Complementation Test
fungi
food and beverages
Cell Biology
Transport inhibitor
biology.organism_classification
Drug Resistance, Multiple
Cell biology
Protein Transport
chemistry
Nitrobenzoates
Mutation
Polar auxin transport
Basipetal auxin transport
Research Article
Subjects
Details
- ISSN :
- 10404651
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- The Plant Cell
- Accession number :
- edsair.doi.dedup.....5f424a1b264fd6f91201c1569121571d