Chemical shift assignments of retinal guanylyl cyclase activating protein 5 (GCAP5)

Authors :: Diana Cudia
James B. Ames
Source :: Biomolecular NMR assignments, vol 13, iss 1
Publication Year :: 2019
Publisher :: eScholarship, University of California, 2019.
Abstract: Retinal membrane guanylyl cyclase (RetGC) in photoreceptor rod and cone cells is regulated by a family of guanylyl cyclase activating proteins (GCAP1-7). GCAP5 is expressed in zebrafish photoreceptors and promotes Ca(2+)-dependent regulation of RetGC enzymatic activity that regulates visual phototransduction. We report NMR chemical shift assignments of the Ca(2+)-free activator form of GCAP5 (BMRB no. 27705).

Subjects :: Protein Structure
Secondary
genetic structures
Nuclear Magnetic Resonance
1.1 Normal biological development and functioning
030303 biophysics
Biophysics
EF-hand
Eye
Biochemistry
Protein Structure, Secondary
Article
Retina
03 medical and health sciences
chemistry.chemical_compound
Structural Biology
Underpinning research
RetGC
GCAP5
Animals
Guanylyl Cyclase Activating Proteins
Amino Acid Sequence
Nuclear Magnetic Resonance, Biomolecular
Zebrafish
Eye Disease and Disorders of Vision
030304 developmental biology
chemistry.chemical_classification
0303 health sciences
Retinal guanylyl cyclase
biology
Activator (genetics)
EF hand
Neurosciences
Retinal
Zebrafish Proteins
biology.organism_classification
Guanylate Cyclase-Activating Proteins
Cell biology
Enzyme
chemistry
Phototransduction
sense organs
Biochemistry and Cell Biology
Guanylate cyclase
Visual phototransduction
Biomolecular
Biotechnology

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