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Case of recurrent refractory nephrotic syndrome in a Japanese boy with COVID‐19
- Source :
- Pediatric Nephrology (Berlin, Germany)
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background There is little information about Coronavirus Disease 2019 (COVID-19) in children with underlying chronic renal pathologies. Cases report From March until April 15, 2020, 16 children with chronic renal pathologies were diagnosed with COVID-19 in Spain. Of these, 6 had end-stage kidney disease (ESKD) (3 transplant recipients and 3 on chronic hemodialysis). The severity of symptoms was mild in all the patients, with little radiological involvement. Three patients were asymptomatic. Fever and upper respiratory symptoms were the most frequent findings. Basal glomerular filtration worsened in 3 patients; however, recovery was rapidly achieved with rehydration and drug dose adjustment. In 2 patients diagnosed with steroid-dependent nephrotic syndrome, COVID-19 provoked a disease relapse. None required oxygen therapy, and 7 could be managed as outpatients. Conclusions COVID-19 disease appears to have a similar clinical course in children with underlying chronic renal pathologies, even in immunosuppressed cases, as in healthy children of the same age; however, special attention must be paid to fluid management and drug dose adjustment.
- Subjects :
- Male
Pediatrics
medicine.medical_specialty
Nephrotic Syndrome
Coronavirus disease 2019 (COVID-19)
SARS-CoV-2
business.industry
Brief Report
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
COVID-19
Mycophenolic Acid
medicine.disease
Japan
Refractory
Recurrence
Pediatrics, Perinatology and Child Health
CKD
Humans
Medicine
business
Children
Nephrotic syndrome
Immunosuppression
Subjects
Details
- ISSN :
- 1442200X and 13288067
- Volume :
- 64
- Database :
- OpenAIRE
- Journal :
- Pediatrics International
- Accession number :
- edsair.doi.dedup.....5eec641cf513931433ceb5649910f675