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Cumulative radiation exposure from imaging procedures and associated lifetime cancer risk for patients with lymphoma

Authors :
Stefan O. Schoenberg
Stefan Klein
E. A. Nekolla
C Hagelstein
Henning D. Popp
Gunnar Brix
Gerhard Glatting
Grete Fabritius
Wolf K. Hofmann
Mathias Meyer
Thomas Henzler
Source :
Scientific Reports
Publication Year :
2016
Publisher :
Nature Publishing Group, 2016.

Abstract

The aim of this study was to systematically evaluate the cumulative radiation exposure and the associated lifetime-cancer-risk from diagnostic imaging in patients with Hodgkin-lymphoma-(HL) or diffuse-large-B-cell-lymphoma (DLBCL). 99 consecutive patients (53-males) diagnosed with HL or DLBCL were included in the study and followed. Based on the imaging reports, organ and effective-doses-(ED) were calculated individually for each patient and the excess lifetime risks were estimated. The average ED in the first year after diagnosis was significantly different for men (59 ± 33 mSv) and women (744 ± 33 mSv)-(p 0.05). Over all years, more than 90% of the ED resulted from CT. The average cumulative radiation risk estimated for the first year was significantly lower for men (0.76 ± 0.41%) as compared to women (1.28 ± 0.54%)-(p

Details

Language :
English
ISSN :
20452322
Database :
OpenAIRE
Journal :
Scientific Reports
Accession number :
edsair.doi.dedup.....5eba14d8d03fac74d434a11752010159
Full Text :
https://doi.org/10.1038/srep35181