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Co-existence of peripheral neuropathy secondary to lead poisoning and chronic polymyositis: Case report
- Source :
- Revista Colombiana de Reumatología, Volume: 23, Issue: 3, Pages: 213-217, Published: SEP 2016
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Se reporta el caso de un hombre de 47 arios con intoxicación crónica por plomo, secundaria a exposición laboral de 5 años, con sintomatología típica de saturnismo. Consultó por debilidad muscular generalizada, disfagia y parestesias en extremidades. Se documentaron altos niveles de plomo en sangre, asociados a neuropatía periférica, confirmada por electromiografía, y disminución de la fuerza muscular en cintura escapular y pélvica (deltoides y vasto medial), así como atrofia de músculos del cuello (flexores y extensores) manifestada como cefaloparesia. Adicional al cuadro de saturnismo se diagnosticó miopatía inflamatoria con base en la elevación de enzimas musculares, miositis por resonancia magnética nuclear y biopsia muscular compatible, siendo, hasta donde se sabe, el primer reporte conocido de la coexistencia de estas 2 enfermedades. A case is presented on a 47-year-old man with chronic lead poisoning with typical symptoms after 5 years of occupational exposure. He consulted for generalised muscle weakness, early dysphagia, cephaloparesia, and paresthesias in upper and lower limbs. He also had atrophy and decreased proximal muscle strength (deltoid and medial vast) and in both flexor and extensor muscles of the neck. He had a history of high blood lead levels and peripheral neuropathy documented by electromyography. In addition to the diagnosis of lead poisoning, inflammatory myopathy was confirmed based on muscle enzyme elevation, muscular inflammation in magnetic resonance imaging, and typical findings in a muscle biopsy. To our knowledge, this is the first report where both conditions are documented in one patient.
- Subjects :
- medicine.medical_specialty
Lead poisoning
Peripheral nervous system diseases
Generalized muscle weakness
Polymyositis
Inflammatory myopathy
03 medical and health sciences
0302 clinical medicine
Atrophy
medicine
Enfermedades del sistema nervioso periférico
Muscle biopsy
medicine.diagnostic_test
business.industry
Intoxicación por plomo
General Medicine
medicine.disease
Surgery
Polimiositis
Peripheral neuropathy
030220 oncology & carcinogenesis
Anesthesia
Proximal Muscle
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 24444405
- Volume :
- 23
- Database :
- OpenAIRE
- Journal :
- Revista Colombiana de Reumatología (English Edition)
- Accession number :
- edsair.doi.dedup.....5e61da1be88b0b882a8388457705c44a
- Full Text :
- https://doi.org/10.1016/j.rcreue.2016.09.002