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Reference high‐resolution manometry values after magnetic sphincter augmentation
- Source :
- Neurogastroenterology and Motility
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Background Magnetic sphincter augmentation (MSA) is an innovative antireflux procedure that can improve lower esophageal sphincter (LES) competency and reduce symptoms of gastroesophageal reflux disease (GERD). Some patients report postoperative dysphagia. To date, no studies have described reference high‐resolution manometry (HRM) values after MSA implantation. Methods High‐resolution manometry was performed in patients free of dysphagia after MSA with or without concurrent crura repair. Reference values for all parameters of the Chicago Classification were defined as those between the 5th and 95th percentiles. The contribution of concurrent crura repair to LES competency and to reference values was also analyzed. Key Results Eighty‐four patients met the study inclusion criteria. The upper limit of normality for integrated relaxation pressure (IRP) and intrabolus pressure (IBP) was 20.2 mmHg and 30.3 mmHg, respectively. Both variables were higher after MSA compared to normative Chicago Classification v3.0 values. The Distal Contractile Integral upper limit was in the range of normality. Patients undergoing crura repair had a significantly higher IRP (p = 0.0378) and lower GERDQ‐A scores (p = 0.0374) and Reflux Symptom Index (p = 0.0030) compared to those who underwent MSA device implantation alone. Conclusion & Inferences This study provides HRM reference values for patients undergoing successful MSA implantation. Crural repair appears to be a key component of LES augmentation and is associated with improved clinical outcomes.<br />Upper limit of normality for IRP and intrabolus pressure was higher after magnetic sphincter augmentation compared to normative Chicago v3.0 values. Patients in whom crura repair was part of the surgical procedure had a significantly higher IRP and better control of reflux symptoms.
- Subjects :
- medicine.medical_specialty
Manometry
Physiology
Esophageal Sphincter, Lower
03 medical and health sciences
0302 clinical medicine
Reference Values
Internal medicine
otorhinolaryngologic diseases
medicine
Humans
In patient
High resolution manometry
Endocrine and Autonomic Systems
business.industry
Magnetic Phenomena
Gastroenterology
Reflux
Original Articles
medicine.disease
crural repair
Dysphagia
integrated relaxation pressure
normative values
medicine.anatomical_structure
magnetic sphincter augmentation
Postoperative dysphagia
high‐resolution manometry
030220 oncology & carcinogenesis
Reference values
Gastroesophageal Reflux
intrabolus pressure
GERD
Cardiology
Sphincter
Original Article
030211 gastroenterology & hepatology
medicine.symptom
Deglutition Disorders
business
Chicago Classification
Subjects
Details
- ISSN :
- 13652982 and 13501925
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Neurogastroenterology & Motility
- Accession number :
- edsair.doi.dedup.....5e373a438d3a90ff999a03efedb975c6