Efficacy and safety of dronedarone by atrial fibrillation history duration: Insights from the <scp>ATHENA</scp> study

Authors :: Valérie Corp dit Genti
Nassir F. Marrouche
Carina Blomström-Lundqvist
Mattias Wieloch
Stuart J. Connolly
Stefan H. Hohnloser
Andrew Koren
Source :: Clinical Cardiology
Publication Year :: 2020
Publisher :: Wiley, 2020.
Abstract: Background: Atrial fibrillation/atrial flutter (AF/AFL) burden increases with increasing duration of AF/AFL history. Hypothesis: Outcomes with dronedarone may also be impacted by duration of AF/AFL history. Methods: In this post hoc analysis of ATHENA, efficacy and safety of dronedarone vs placebo were assessed in groups categorized by time from first known AF/AFL episode to randomization (ie, duration of AF/AFL history)

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