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Undifferentiated sarcoma of the liver: a rare pediatric tumor
- Source :
- Annals of Saudi Medicine, Vol 32, Iss 2, Pp 203-205 (2012)
- Publication Year :
- 2012
- Publisher :
- King Faisal Specialist Hospital and Research Centre, 2012.
-
Abstract
- Undifferentiated embryonal sarcoma of the liver (UESL) is an uncommon hepatic tumor of mesenchymal origin recognized as a unique clinicopathologic entity since 1978. UESL has historically been considered an aggressive neoplasm with an unfavorable prognosis. Survival has improved using recent multimodal approaches, designed for patients with soft tissue sarcomas at other sites. Several small series have reported survival of up to 70% of children. We report a case of a 12-year-old boy from the United Arab Emirates who relapsed after complete surgical resection and was then successfully treated with re-resection followed by chemotherapy and radiotherapy. With a follow-up of 5 years, he is well and asymptomatic, and is leading a healthy life. This case emphasizes the fact that these poorly prognostic tumors may benefit from post-surgery chemotherapy. This case illustrates the improved survival of UESL patients following the multimodality therapy with a relatively long follow-up. This is the first case of UESL reported in this region of the world.
- Subjects :
- Male
Reoperation
medicine.medical_specialty
medicine.medical_treatment
lcsh:Medicine
Multimodality Therapy
Asymptomatic
medicine
Undifferentiated (Embryonal) Sarcoma
Neoplasm
Combined Modality Therapy
Humans
Child
Chemotherapy
business.industry
Liver Neoplasms
lcsh:R
Soft tissue
Sarcoma
General Medicine
medicine.disease
Radiation therapy
Radiology
medicine.symptom
Neoplasm Recurrence, Local
business
Subjects
Details
- Language :
- English
- ISSN :
- 09754466 and 02564947
- Volume :
- 32
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Annals of Saudi Medicine
- Accession number :
- edsair.doi.dedup.....5df2e3b5f5f38709642235ab74e7adc7