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Strain and elasticity imaging in compression optical coherence elastography: The two-decade perspective and recent advances
- Source :
- Journal of biophotonicsREFERENCES. 14(2)
- Publication Year :
- 2020
-
Abstract
- Quantitative mapping of deformation and elasticity in optical coherence tomography has attracted much attention of researchers during the last two decades. However, despite intense effort it took ~15 years to demonstrate optical coherence elastography (OCE) as a practically useful technique. Similarly to medical ultrasound, where elastography was first realized using the quasi-static compression principle and later shear-wave-based systems were developed, in OCE these two approaches also developed in parallel. However, although the compression OCE (C-OCE) was proposed historically earlier in the seminal paper by J. Schmitt in 1998, breakthroughs in quantitative mapping of genuine local strains and the Young's modulus in C-OCE have been reported only recently and have not yet obtained sufficient attention in reviews. In this overview, we focus on underlying principles of C-OCE; discuss various practical challenges in its realization and present examples of biomedical applications of C-OCE. The figure demonstrates OCE-visualization of complex transient strains in a corneal sample heated by an infrared laser beam.
- Subjects :
- Computer science
General Physics and Astronomy
01 natural sciences
General Biochemistry, Genetics and Molecular Biology
010309 optics
Cornea
Optical coherence elastography
Optical coherence tomography
Elastic Modulus
0103 physical sciences
medicine
Electronic engineering
General Materials Science
Medical ultrasound
medicine.diagnostic_test
010401 analytical chemistry
Perspective (graphical)
General Engineering
General Chemistry
Elasticity (physics)
Compression (physics)
Elasticity
0104 chemical sciences
Elasticity Imaging Techniques
Elastography
Infrared laser beam
Tomography, Optical Coherence
Subjects
Details
- ISSN :
- 18640648
- Volume :
- 14
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of biophotonicsREFERENCES
- Accession number :
- edsair.doi.dedup.....5dc2e56273cb0045929b33c44da82ca0