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Role of Circular RNA in Kidney-Related Diseases
- Source :
- Frontiers in Pharmacology, Frontiers in Pharmacology, Vol 12 (2021)
- Publication Year :
- 2021
- Publisher :
- Frontiers Media S.A., 2021.
-
Abstract
- The kidney is vital in maintaining fluid, electrolyte, and acid–base balance. Kidney-related diseases, which are an increasing public health issue, can happen to people of any age and at any time. Circular RNAs (circRNAs) are endogenous RNA that are produced by selective RNA splicing and are involved in progression of various diseases. Studies have shown that various kidney diseases, including renal cell carcinoma, acute kidney injury, and chronic kidney disease, are linked to circRNAs. This review outlines the characteristics and biological functions of circRNAs and discusses specific studies that provide insights into the function and potential of circRNAs for application in the diagnosis and treatment of kidney-related diseases.
- Subjects :
- Pharmacology
Kidney
renal cell carcinoma
business.industry
urogenital system
lcsh:RM1-950
Acute kidney injury
EMT
RNA
medicine.disease
Bioinformatics
chronic kidney diseases
medicine.anatomical_structure
lcsh:Therapeutics. Pharmacology
acute kidney injury
Renal cell carcinoma
Circular RNA
RNA splicing
medicine
Pharmacology (medical)
Systematic Review
circRNAs
business
Function (biology)
Kidney disease
Subjects
Details
- Language :
- English
- ISSN :
- 16639812
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- Frontiers in Pharmacology
- Accession number :
- edsair.doi.dedup.....5dc182c39451b8075e4f23aff52a77f7