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Comparison of 5‐year postoperative outcomes after Billroth I and Roux‐en‐Y reconstruction following distal gastrectomy for gastric cancer: Results from a multi‐institutional randomized controlled trial
- Source :
- Annals of Gastroenterological Surgery, Vol 5, Iss 1, Pp 93-101 (2021), Annals of Gastroenterological Surgery
- Publication Year :
- 2021
- Publisher :
- Wiley, 2021.
-
Abstract
- Aim We previously reported in a randomized controlled trial that Billroth I and Roux‐en‐Y reconstructions were generally equivalent regarding body weight change and nutritional status 1 year after distal gastrectomy for gastric cancer. We describe the long‐term follow‐up data 5 years after distal gastrectomy. Methods We analyzed consecutive gastric cancer patients who were randomly assigned to undergo Billroth I or Roux‐en‐Y reconstruction after distal gastrectomy. We evaluated body weight change, nutritional status, late complications, quality of life (QOL) using the European Organization for Research and Treatment of Cancer Core QOL Questionnaire, and dysfunction using the Dysfunction After Upper Gastrointestinal Surgery for Cancer, 5 years after surgery. Results A total of 228 patients (Billroth I = 105; Roux‐en‐Y = 123) were eligible for efficacy analyses in this study. Body weight loss 5 years after surgery did not differ significantly between the Billroth I and Roux‐en‐Y groups (10.0% ± 7.9% and 9.6% ± 8.4%, respectively; P = .70). There were no significant differences in other aspects of nutritional status between the two groups. Reflux esophagitis occurred in 19.0% of the patients in the Billroth I group vs 4.9% in the Roux‐en‐Y group (P = .002). Regarding QOL, Billroth I was significantly inferior to Roux‐en‐Y on the diarrhea scale (Billroth I: 28.6, Roux‐en‐Y: 16.0; P = .047). Regarding dysfunction, no score differed significantly between the two groups. Conclusions Billroth I and Roux‐en‐Y reconstructions were generally equivalent regarding body weight change, nutritional status, and QOL 5 years after distal gastrectomy, although Roux‐en‐Y more effectively prevented reflux esophagitis and diarrhea.<br />Billroth I and Roux‐en‐Y reconstructions were generally equivalent regarding body weight change, nutritional status, and quality of life 5 years after distal gastrectomy, excluding reflux esophagitis and diarrhea.
- Subjects :
- medicine.medical_specialty
RD1-811
medicine.medical_treatment
Distal gastrectomy
RC799-869
Gastroenterology
Roux‐en‐Y reconstruction
law.invention
body weight
Randomized controlled trial
Quality of life
law
distal gastrectomy
Internal medicine
medicine
Billroth I
Reflux esophagitis
business.industry
gastric cancer
Cancer
Original Articles
Billroth I reconstruction
Diseases of the digestive system. Gastroenterology
medicine.disease
Roux-en-Y anastomosis
humanities
Diarrhea
Original Article
Surgery
medicine.symptom
business
Subjects
Details
- Language :
- English
- ISSN :
- 24750328
- Volume :
- 5
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Annals of Gastroenterological Surgery
- Accession number :
- edsair.doi.dedup.....5d6b47a3d1151cc5bada161245c1fe8f