Back to Search
Start Over
Synthesis and Characterization of Surface Modified, Fluorescent and Biocompatible ZnS Nanoparticles with a Hydrophobic Chitosan Derivative
- Source :
- Journal of Fluorescence. 27:1277-1284
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- The introduction of a hydrophobic moiety on chitosan enhances the self-assembling properties, mucoadhesion, the permeability of the macromolecule and aids in target specific delivery. Our group synthesized a hydrophobic trans N-(6,6-Dimethyl-2-hepten-4-ynyl)chitosan derivative (CSD) and studied the surface modification of ZnS nanoparticles in a single pot reaction. X-ray diffraction studies and FESEM imaging confirms the nano size and morphology of the surface modified Zinc sulfide nanoparticles (ZnS-CSD NPs). The proposed ZnS-CSD NPs showed excellent emission at 457 nm. Photostability studies indicate that the surface modified ZnS-CSD NPs possess better photostability than Rhodamine B and FITC. Cell viability tests confirmed the biocompatibility of the modified nanoparticles. All these features of ZnS- CSD NPs makes these candidates an excellent choice in a wide range of in vitro or in vivo studies as fluorescent biological labels.
- Subjects :
- Sociology and Political Science
Biocompatibility
Clinical Biochemistry
Nanoparticle
Nanotechnology
02 engineering and technology
010402 general chemistry
01 natural sciences
Biochemistry
Chitosan
chemistry.chemical_compound
Rhodamine B
Mucoadhesion
Spectroscopy
technology, industry, and agriculture
021001 nanoscience & nanotechnology
Zinc sulfide
0104 chemical sciences
Clinical Psychology
chemistry
Chemical engineering
Surface modification
0210 nano-technology
Law
Social Sciences (miscellaneous)
Macromolecule
Subjects
Details
- ISSN :
- 15734994 and 10530509
- Volume :
- 27
- Database :
- OpenAIRE
- Journal :
- Journal of Fluorescence
- Accession number :
- edsair.doi.dedup.....5d68ea85b26afd478e70f847c9f4b932