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Uso precoz de la eritropoyetina en la prevención de la anemia del prematuro
- Source :
- Revista médica de Chile v.128 n.12 2000, SciELO Chile, CONICYT Chile, instacron:CONICYT
- Publication Year :
- 2000
- Publisher :
- SciELO Agencia Nacional de Investigacion y Desarrollo (ANID), 2000.
-
Abstract
- Background: Anemia is common among very low birth weight newborns and requires frequent blood tranfusions. Erythropoietin was been reported to be useful in the prevention of this anemia. Aim: To asses the benefits of early (before the third week of life) Human recombinant Erythropoietin (r-EPO) administration to reduce the requirement of blood tranfusions in very low birth weight newborns. Patients and methods: sixty newborns under 1500g of birthweight were randomly assigned to recive r-EPO (n=29) or placebo (n=31) three times per week, during four weeks. Packed red cell volume and reticulocyte counts were measured weekly. Serum erythropoietin was measured prior to eigth dose. Transfusion requirements were recorded. Results: r-EPO reduced transfusions from 1.41 ± 1.1 to 0.69 ± 1 transfusions/newborns (p
- Subjects :
- Gynecology
Pediatrics
medicine.medical_specialty
Anemia
business.industry
Infant, low birth weight
General Medicine
medicine.disease
Placebo
Anemia neonatal
law.invention
Low birth weight
medicine.anatomical_structure
Reticulocyte
Randomized controlled trial
Reticulocyte count
Erythropoietin
law
hemic and lymphatic diseases
medicine
Active treatment
medicine.symptom
business
medicine.drug
Subjects
Details
- ISSN :
- 00349887
- Volume :
- 128
- Database :
- OpenAIRE
- Journal :
- Revista médica de Chile
- Accession number :
- edsair.doi.dedup.....5d3f638fbee25e9d2b9ed791361e6517