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Multidisciplinary approach in the management of advanced ovarian cancer patients: A personalized approach. Results from a specialized ovarian cancer unit
- Source :
- Gynecologic oncology. 144(3)
- Publication Year :
- 2016
-
Abstract
- Objective The aim of the present study was to evaluate the impact of a multidisciplinary approach in patients' selection with advanced ovarian cancer (AOC) for different therapeutic strategies. Methods Patients referred at our institution between 2009 and 2012 for AOC were included. Primary multidisciplinary evaluation was performed in all patients. Different strategies included: 1. patients referred to primary neoadjuvant chemotherapy (NACT) and interval surgery (IDS) (group A); 2. patients considered for surgical exploration. After surgical exploration, patients were either considered for primary debulking (PDS; group B), or NACT (group C). Results A total of 363 patients were included. Of 38 patients (10.5%) in group A, 24 (63%) had sovradiaphragmatic/multiple liver metastases; 14 (37%) were excluded for PDS for anestehesiologic/medical reasons. Of 325 (89.5%) considered for surgical exploration, 295 (91%; group B) had primary surgery with debulking intent (N: 277) and were cytoreduced to no macroscopic disease (R0: N:200; 68%) o minimal RD
- Subjects :
- Adult
medicine.medical_specialty
medicine.medical_treatment
Disease
Group B
03 medical and health sciences
Young Adult
0302 clinical medicine
Obstetrics and gynaecology
medicine
Humans
030212 general & internal medicine
Young adult
Precision Medicine
Aged
Aged, 80 and over
Ovarian Neoplasms
Chemotherapy
business.industry
Obstetrics and Gynecology
Middle Aged
Debulking
medicine.disease
Precision medicine
Surgery
Oncology
030220 oncology & carcinogenesis
Female
business
Ovarian cancer
Subjects
Details
- ISSN :
- 10956859
- Volume :
- 144
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Gynecologic oncology
- Accession number :
- edsair.doi.dedup.....5d2e1bab2be9a4f0c5beaf3adc60c368