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Reinforcement effects of Boschniakia rossica on discrimination learning in cholinergic lesions of rats
- Source :
- Journal of ethnopharmacology. 44(2)
- Publication Year :
- 1994
-
Abstract
- The dried herb or stem of Boschniakia rossica (Boschniakiae Herba) has been used as an antisenile agent in the Jilin Province of China. To elucidate the effects of Boschniakiae Herba on decreased learning ability and memory weakness, a 50% ethanol extract of Boschniakiae Herba was administered to rats whose nucleus basalis of Meynert had been destroyed by the injection of ibotenic acid. This administration showed a significant improvement in the decrease of the ratio of correct responses caused by destruction of the nucleus basalis of Meynert. These results suggest that B. rossica would be therapeutic in senility.
- Subjects :
- Pharmacology
Male
biology
Traditional medicine
Plant Extracts
Boschniakia rossica
Pharmacognosy
biology.organism_classification
Nucleus basalis
law.invention
Rats
Discrimination Learning
chemistry.chemical_compound
chemistry
Substantia Innominata
law
Oral administration
Drug Discovery
Cholinergic
Animals
Discrimination learning
Medicine, Chinese Traditional
Phytotherapy
Ibotenic acid
Subjects
Details
- ISSN :
- 03788741
- Volume :
- 44
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Journal of ethnopharmacology
- Accession number :
- edsair.doi.dedup.....5d2b204c150759c337734b09ddaaf0bd