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RNA with chemotherapeutic base analogues as a dual-functional anti-cancer drug

Authors :
Jarzebska, Natalia Teresa
Tusup, Marina
Frei, Julia
Weiss, Tobias
Holzinger, Tim
Mellett, Mark
Diken, Mustafa
Bredl, Simon
Weller, Michael
Speck, Roberto F
Kündig, Thomas M
Sahin, Ugur
Pascolo, Steve
University of Zurich
Pascolo, Steve
Source :
OncoImmunology. 11
Publication Year :
2022
Publisher :
Informa UK Limited, 2022.

Abstract

Nanoparticles of different sizes formulated with unmodified RNA and Protamine differentially engage Toll-like Receptors (TLRs) and activate innate immune responses

Details

ISSN :
2162402X
Volume :
11
Database :
OpenAIRE
Journal :
OncoImmunology
Accession number :
edsair.doi.dedup.....5ce444486e7f9b310199224fb1635e34