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Prognostic value of inferior mesenteric artery lymph node metastasis in cancer of the descending colon, sigmoid colon and rectum
- Source :
- Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland. 20(6)
- Publication Year :
- 2017
-
Abstract
- AIM This study aimed to analyse the potential significance of metastasis to the inferior mesenteric artery lymph node (IMA-LN) in patients with malignancy of the left colon and rectum. METHOD A retrospective analysis of a cohort of 890 patients collected prospectively who underwent radical resection of a primary tumour of the descending colon, sigmoid colon and rectum in our department from 1 January 2009 to 31 December 2015 was performed. Patients were divided into an IMA-LN metastasis (IMA-LN (+)) group (n = 51) and a non IMA-LN metastasis (IMA-LN (-)) group (n = 839). A total of 801 patients were followed by a designated member of the study staff. Clinical features, pathological characteristics, recurrence patterns and survival rates were compared between the two groups. RESULTS In the IMA-LN (+) group, the risk ratio of overall recurrence and tumour related death was 7.786 (95% CI 4.142-14.637) and 7.756 (95% CI 4.142-14.525) respectively. Significant differences were found in overall survival (log-rank: χ2 = 69.06, P
- Subjects :
- Adult
Male
medicine.medical_specialty
Rectum
Kaplan-Meier Estimate
Adenocarcinoma
Malignancy
Inferior mesenteric artery
Gastroenterology
Disease-Free Survival
Descending colon
Metastasis
03 medical and health sciences
0302 clinical medicine
Colon, Sigmoid
medicine.artery
Internal medicine
medicine
Humans
Mesentery
Lymph node
Aged
Neoplasm Staging
Proportional Hazards Models
Retrospective Studies
Aged, 80 and over
business.industry
Sigmoid colon
Mesenteric Artery, Inferior
Middle Aged
medicine.disease
Prognosis
Adenocarcinoma, Mucinous
Survival Analysis
Colon, Descending
Survival Rate
medicine.anatomical_structure
030220 oncology & carcinogenesis
Lymphatic Metastasis
Multivariate Analysis
Colon neoplasm
Lymph Node Excision
030211 gastroenterology & hepatology
Female
Lymph Nodes
business
Colorectal Neoplasms
Subjects
Details
- ISSN :
- 14631318
- Volume :
- 20
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
- Accession number :
- edsair.doi.dedup.....5c4e4743ef2a4903cdaf16218631ea09