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The Screening of Nails for Selected Essential and Toxic Elements in Normotensive and Pre-Eclamptic Women
- Source :
- Biological trace element research. 189(1)
- Publication Year :
- 2018
-
Abstract
- To compare the concentrations of 13 different elements in nail samples from pre-eclamptic and normotensive pregnant women. The study site was a regional hospital in Durban, KwaZulu Natal. Nail samples were collected from normotensive (n = 33) and pre-eclamptic (n = 33) pregnant women. Approximately 0.02 g of nail samples were digested in 70% nitric acid and analyzed using inductively coupled plasma-optical emission spectrometry. Analytes of interest were the following essential elements calcium (Ca), chromium (Cr), cobalt (Co), copper (Cu), iron (Fe), magnesium (Mg), manganese (Mn), nickel (Ni), selenium (Se) and Zinc (Zn) as well as toxic elements, arsenic (As), cadmium (Cd) and lead (Pb). The observed concentrations of bioelements (mean, μg/g), Ca: normotensive (N) 3467 ± 197 vs (PE) 2897 ± 190; Mg: (N) 736 ± 61 vs (PE) 695 ± 59, were lower in pre-eclampsia albeit not statistically significant. Similarly, the observed concentrations of bioelements (mean, μg/g), Cd: (N) 3 ± 0.3 vs (PE) 2 ± 0.4; Co: (N) 3 ± 0.3 (PE) not detected; Mn: (N) 7 ± 1 (PE) 4 ± 0.8, were significantly lower in pre-eclampsia (p = 0.004, 0.0001 and 0.022, respectively). Therefore, this study demonstrated significantly lower levels of Cd, Co and Mn in pre-eclampsia which justifies the need for further research on these elements towards the effective management or prevention of pre-eclampsia which could ultimately also aid in establishing its pathogenesis.
- Subjects :
- Adult
Chromium
Endocrinology, Diabetes and Metabolism
Iron
Clinical Biochemistry
chemistry.chemical_element
Blood Pressure
Manganese
Zinc
010501 environmental sciences
Calcium
In Vitro Techniques
01 natural sciences
Biochemistry
Arsenic
Inorganic Chemistry
03 medical and health sciences
Selenium
Young Adult
Animal science
Pre-Eclampsia
Nickel
Pregnancy
Humans
Magnesium
0105 earth and related environmental sciences
0303 health sciences
Cadmium
030302 biochemistry & molecular biology
Biochemistry (medical)
General Medicine
Cobalt
Trace Elements
chemistry
Nails
Female
Copper
Subjects
Details
- ISSN :
- 15590720
- Volume :
- 189
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Biological trace element research
- Accession number :
- edsair.doi.dedup.....5c1d6c4ba0893ed3dc77729c847076e9