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Supplementary Tables S1-5 from Resistance to CDK2 Inhibitors Is Associated with Selection of Polyploid Cells in CCNE1-Amplified Ovarian Cancer

Authors :
David D. Bowtell
Lynda J. Campbell
Carleen Cullinane
Gad Getz
Paul M. Waring
William C. Hahn
Danny Rischin
Linda Mileshkin
Irma Gresshoff
Scott Carter
Barbara A. Weir
Sarah Ftouni
Joshy George
Crisoula Batzios
Elizabeth Loehrer
Maya Kansara
Chris Mitchell
Meaghan Wall
George Au-Yeung
Dariush Etemadmoghadam
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Tables S1-5 - PDF filr 185K, Supplementary Table S1: Essentiality of CDKs in CCNE1 amplified cell lines; Supplementary Table S2: GeneGo gene expression pathways enriched in PHA-533533 resistant cell lines; Supplementary Table S3: Copy number changes identified by SNP microarray in PHA-533533 resistant cell lines; Supplementary Table S4: Gene Set Enrichment Analysis (GSEA) of positional gene sets enriched in amplified or deleted genes specific to PHA-533533 resistant cells; Supplementary Table S5: OVCAR-3 cell line and derivative resistant line karyotypes

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....5c16e9ff97962327061fcd59e3079b1c
Full Text :
https://doi.org/10.1158/1078-0432.22449200