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De Novo Malignancy After Solid Organ Transplantation in Children
- Source :
- Transplantation Proceedings. 41:674-675
- Publication Year :
- 2009
- Publisher :
- Elsevier BV, 2009.
-
Abstract
- The aim of this study was to assess the prevalence of de novo malignancy after solid organ transplantation in childhood. A retrospective questionnaire-based survey was sent to 9 referral centers for pediatric organ transplantation in France. Among 1326 children who underwent solid organ transplantation since 1996, 80 (6%) presented with de novo malignancy posttransplantation during childhood: posttransplant lymphoproliferative disease was the most common (5% of pediatric recipients) comprising 80% of all tumors, with a disproportionately high prevalence among combined liver and small bowel recipients (18%). Various solid tumors were observed mainly among kidney recipients. No skin cancer was reported.
- Subjects :
- medicine.medical_specialty
Pediatrics
medicine.medical_treatment
Lymphoproliferative disorders
Liver transplantation
Organ transplantation
Neoplasms
Surveys and Questionnaires
Intestine, Small
Prevalence
medicine
Humans
Child
Retrospective Studies
Transplantation
Kidney
business.industry
Incidence
Incidence (epidemiology)
Retrospective cohort study
Organ Transplantation
medicine.disease
Lymphoproliferative Disorders
Liver Transplantation
Surgery
medicine.anatomical_structure
Skin cancer
business
Subjects
Details
- ISSN :
- 00411345
- Volume :
- 41
- Database :
- OpenAIRE
- Journal :
- Transplantation Proceedings
- Accession number :
- edsair.doi.dedup.....5b86f05dda10d1c234f4d95e15944b2f
- Full Text :
- https://doi.org/10.1016/j.transproceed.2008.12.020