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De Novo Malignancy After Solid Organ Transplantation in Children

Authors :
Marina Charbit
D. Debray
C. Guyot
J. Harambat
C. Rivet
F. Iserin
V. Baudouin
S. Di Filippo
F. Lacaille
Source :
Transplantation Proceedings. 41:674-675
Publication Year :
2009
Publisher :
Elsevier BV, 2009.

Abstract

The aim of this study was to assess the prevalence of de novo malignancy after solid organ transplantation in childhood. A retrospective questionnaire-based survey was sent to 9 referral centers for pediatric organ transplantation in France. Among 1326 children who underwent solid organ transplantation since 1996, 80 (6%) presented with de novo malignancy posttransplantation during childhood: posttransplant lymphoproliferative disease was the most common (5% of pediatric recipients) comprising 80% of all tumors, with a disproportionately high prevalence among combined liver and small bowel recipients (18%). Various solid tumors were observed mainly among kidney recipients. No skin cancer was reported.

Details

ISSN :
00411345
Volume :
41
Database :
OpenAIRE
Journal :
Transplantation Proceedings
Accession number :
edsair.doi.dedup.....5b86f05dda10d1c234f4d95e15944b2f
Full Text :
https://doi.org/10.1016/j.transproceed.2008.12.020