Additional file 1 of Clinical application and evaluation of metagenomic next-generation sequencing in suspected adult central nervous system infection

Additional file 1: Table S1. Commonly reported pathogens in central nervous system (CNS) Infection. Table S2. Criteria of CNS infection. Table S3. Missed or extra identified bacteria and fungi by mNGS when comparing to culture in CNS infections. Table S4. The consistency between mNGS and other conventional methods (PCR, Xpert MTB/RIF, Filmarray, serological antibody test and etc.). Table S5. The comparison of relative abundance of pathogens who were detected at least 5 times between a) culture-positive vs culture-negative and b) with vs without empirical treatment patients. Table S6. The CSF laboratory examinations among different subgroups.