Back to Search
Start Over
CENTRAL SEROUS CHORIORETINOPATHY IN POSTMENOPAUSAL WOMEN RECEIVING EXOGENOUS TESTOSTERONE
- Source :
- Retinal casesbrief reports. 11(2)
- Publication Year :
- 2016
-
Abstract
- Central serous chorioretinopathy (CSR) is a serous detachment of the neurosensory retina commonly associated with male sex, Type-A personality and corticosteroid use. Exogenous administration of androgens and development of CSR in men has been reported. Only one case of CSR in a postmenopausal woman receiving exogenous androgen therapy has been reported. The authors describe three cases of chronic CSR in postmenopausal women receiving exogenous testosterone therapy.Diagnosis was based on characteristic clinical, fluorescein angiographic, and optical coherence tomography findings. The three women were being treated with exogenous testosterone and progesterone therapy for symptoms of menopause and libido loss.Average age at presentation was 54.7 years (53-56 years), average duration of exogenous androgen use was 61 months (36-87 months), with average 19.7-month follow-up. Resolution of symptoms seemed correlated with cessation of androgen use despite treatment with oscillatory photodynamic therapy and intravitreal pharmacotherapy with antivascular endothelial growth factor agents.Exogenous testosterone is increasingly prescribed for menopausal symptoms and libido loss. Treatment with oscillatory photodynamic therapy, supplemental bevacizumab intravitreal pharmacotherapy, and cessation of exogenous androgen therapy was successful in three cases of chronic, therapy-resistant CSR. Ophthalmologists should inquire about androgen usage in patients who present with CSR, especially in the setting of therapy resistance.
- Subjects :
- medicine.medical_specialty
Postmenopausal women
endocrine system diseases
business.industry
chemical and pharmacologic phenomena
Testosterone (patch)
General Medicine
Middle Aged
Exogenous testosterone
03 medical and health sciences
Ophthalmology
Serous fluid
0302 clinical medicine
Endocrinology
Central Serous Chorioretinopathy
Internal medicine
030221 ophthalmology & optometry
medicine
Androgens
Humans
Corticosteroid use
Female
Testosterone
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 19371578
- Volume :
- 11
- Issue :
- 2
- Database :
- OpenAIRE
- Journal :
- Retinal casesbrief reports
- Accession number :
- edsair.doi.dedup.....5b19503cbe85ae68888229b705d4bbe8