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Hepatitis C virus quasi-species dynamics predict progression of fibrosis after liver transplantation
- Source :
- The Journal of infectious diseases. 189(11)
- Publication Year :
- 2003
-
Abstract
- Background. The dynamics of hepatitis C virus (HCV) quasi species in the E2 region may correlate with the course of infection after orthotopic liver transplantation (OLT).Methods. Thirty-four patients who underwent transplantation for HCV-related cirrhosis were studied. Serum and liver samples were available before OLT and at 1 week, 4 months, and 1 year after OLT. Patients were divided into group 1 (Knodell/Ishak fibrosis stage [FS] at 1 year
- Subjects :
- Liver Cirrhosis
Male
medicine.medical_specialty
Pathology
Cirrhosis
medicine.medical_treatment
Hepatitis C virus
Hepacivirus
Liver transplantation
medicine.disease_cause
Gastroenterology
Flaviviridae
Viral Envelope Proteins
Fibrosis
Internal medicine
medicine
Immunology and Allergy
Humans
Phylogeny
Polymorphism, Single-Stranded Conformational
biology
Reverse Transcriptase Polymerase Chain Reaction
Genetic Variation
Hepatitis C
Hepatitis C, Chronic
Middle Aged
medicine.disease
biology.organism_classification
Liver Transplantation
Transplantation
surgical procedures, operative
Infectious Diseases
Disease Progression
RNA, Viral
Electrophoresis, Polyacrylamide Gel
Female
5' Untranslated Regions
Subjects
Details
- ISSN :
- 00221899
- Volume :
- 189
- Issue :
- 11
- Database :
- OpenAIRE
- Journal :
- The Journal of infectious diseases
- Accession number :
- edsair.doi.dedup.....5b0082df34d99543b303658a8b5d14c9