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Multifocal spectacles in childhood myopia: Are treatment effects maintained? A systematic review and meta-analysis
- Source :
- Survey of Ophthalmology. 65:239-249
- Publication Year :
- 2020
- Publisher :
- Elsevier BV, 2020.
-
Abstract
- We evaluate the impact of duration on the treatment effect of multifocal spectacle lenses used to inhibit myopia progression in children. A systematic literature search identified randomized controlled trials where multifocal lenses were prescribed as the intervention, with single-vision lenses as the control. Nine randomized control trials involving 1,701 children aged 8–13 years were included in the meta-analysis. Treatment effects, that is, differences in spherical equivalent refraction between intervention and nonintervention groups, were analyzed over both 6- and 12-month intervals. As treatment duration increased, effectiveness reduced. In 6-month intervals, treatment effects were 0.07 D (95 % CI 0.02, 0.13), 0.03 D (95% CI −0.02, 0.08), and 0.02 D (95% CI −0.05, 0.11) for baseline to 6, 6–12, and 12–18 months, respectively. For 12-month intervals, treatment effects were 0.21 D (95% CI 0.12, 0.29), 0.11 D (95% CI 0.03, 0.19), and 0.12 D (95% CI −0.01, 0.25) for baseline to 12, 12–24, and 24–36 months, respectively. Even during the second 6 months of wear, the ability of multifocal spectacle lenses to inhibit myopia progression was reduced. It is not appropriate to extrapolate the treatment effect observed in the first 6 months or 12 months to estimate the likely future benefit of treatment.
- Subjects :
- medicine.medical_specialty
Time Factors
business.product_category
Treatment duration
Visual Acuity
Spherical equivalent
Refraction, Ocular
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
law
Internal medicine
Humans
Medicine
Treatment effect
Child
Multifocal lenses
Spectacle lenses
Multifocal spectacles
business.industry
Ophthalmology
Eyeglasses
Meta-analysis
Myopia, Degenerative
Disease Progression
030221 ophthalmology & optometry
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 00396257
- Volume :
- 65
- Database :
- OpenAIRE
- Journal :
- Survey of Ophthalmology
- Accession number :
- edsair.doi.dedup.....5afb7baeb60cc89d84dfa372260de822