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An update on the role of PET/CT and PET/MRI in ovarian cancer
- Source :
- European journal of nuclear medicine and molecular imaging. 44(6)
- Publication Year :
- 2016
-
Abstract
- This review article summarizes the role of PET/CT and PET/MRI in ovarian cancer. With regard to the diagnosis of ovarian cancer, the presence of FDG uptake within the ovary of a postmenopausal woman raises the concern for ovarian cancer. Multiple studies show that FDG PET/CT can detect lymph node and distant metastasis in ovarian cancer with high accuracy and may, therefore, alter the management to obtain better clinical outcomes. Although PET/CT staging is superior for N and M staging of ovarian cancer, its role is limited for T staging. Additionally, FDG PET/CT is of great benefit in evaluating treatment response and has prognostic value in patients with ovarian cancer. FDG PET/CT also has value to detect recurrent disease, particularly in patients with elevated serum CA-125 levels and negative or inconclusive conventional imaging test results. PET/MRI may beneficial for tumor staging because MRI has higher soft tissue contrast and no ionizing radiation exposure compared to CT. Some non-FDG PET radiotracers such as 18F-fluorothymidine (FLT) or 11C-methionine (MET) have been studied in preclinical and clinical studies as well and may play a role in the evaluation of patients with ovarian cancer.
- Subjects :
- medicine.medical_specialty
Ovary
030218 nuclear medicine & medical imaging
Elevated serum
03 medical and health sciences
0302 clinical medicine
Recurrence
Positron Emission Tomography Computed Tomography
medicine
Humans
Radiology, Nuclear Medicine and imaging
In patient
Lymph node
Neoplasm Staging
Ovarian Neoplasms
PET-CT
business.industry
Fdg uptake
General Medicine
medicine.disease
Prognosis
Magnetic Resonance Imaging
Review article
medicine.anatomical_structure
030220 oncology & carcinogenesis
Female
Radiology
Ovarian cancer
Nuclear medicine
business
Subjects
Details
- ISSN :
- 16197089
- Volume :
- 44
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- European journal of nuclear medicine and molecular imaging
- Accession number :
- edsair.doi.dedup.....5ab7708b03bc237da58e4f52961cf58a