PHYTOCHEMICAL SCREENING AND EVALUATION OF IN VITRO ANTI DIABETIC ACTIVITY OF CATHARANTHUS ROSEUS AND SARACA INDICA

Diabetes mellitus is a metabolic disorder characterized by hyperglycemia resulting from increased hepatic glucose production, diminished insulin secretion and impaired insulin action. Though diabetes is a global problem so the present study aims to open new avenue to explore the antidiabetic activity of various medicinal plants on a firm scientific footing and different market formulation which add value as novel antidiabetic drug. In present Study Catharanthus roseus and Saraca indica was tested on the different standardization criteria such as organoleptic measurement, percentage yield, phytochemical screening, antioxidant and antidiabetic potential. Popularity of naturopathy, nature healing has huge impact on herbal drugs which are extensively used in many herbal formulations in traditional system of medicine. Hence, it is required to standardize the herbal materials in order to check purity of the materials that will serve as reference for further studies. For standardization three features must be checked; authenticity, purity and assay. Indian history of medicinal plants has proven that herbs have been used to treat topical infections. From the long list of herbs in my research Catharanthus roseus and Saraca indica are some of the common herbs that are found in abundant. The chosen plants develop an effective antioxidant and anti-diabetic which is environmentally safe. Key words: Catharanthus roseus, Saraca indica, In vitro antioxidant and anti-diabetic activity