Supplementary Figure 1 from Distinct Genomic Alterations in Prostate Tumors Derived from African American Men

Somatically acquired exon mutations of PIK3CA identified by targeted deeper NGS in PCa of AA/black are compared with those reported in PCa of EA/white in the GDC (upper panel); and CNAs together with B-allele frequency identified by OncoScan (lower panels) in 2 example tumors harboring missense mutation p.I391M. In upper panel, blue = missense, green = synonymous, purple arrow marking a mutation previously reported in AA PCa.