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Young adult outcomes in the follow-up of the multimodal treatment study of attention-deficit/hyperactivity disorder: symptom persistence, source discrepancy, and height suppression
- Source :
- Journal of child psychology and psychiatry, and allied disciplines, vol 58, iss 6, Repositorio EdocUR-U. Rosario, Universidad del Rosario, instacron:Universidad del Rosario
- Publication Year :
- 2016
-
Abstract
- BackgroundThe Multimodal Treatment Study (MTA) began as a 14-month randomized clinical trial of behavioral and pharmacological treatments of 579 children (7-10years of age) diagnosed with attention-deficit/hyperactivity disorder (ADHD)-combined type. It transitioned into an observational long-term follow-up of 515 cases consented for continuation and 289 classmates (258 without ADHD) added as a local normative comparison group (LNCG), with assessments 2-16years after baseline.MethodsPrimary (symptom severity) and secondary (adult height) outcomes in adulthood were specified. Treatment was monitored to age 18, and naturalistic subgroups were formed based on three patterns of long-term use of stimulant medication (Consistent, Inconsistent, and Negligible). For the follow-up, hypothesis-generating analyses were performed on outcomes in early adulthood (at 25years of age). Planned comparisons were used to estimate ADHD-LNCG differences reflecting persistence of symptoms and naturalistic subgroup differences reflecting benefit (symptom reduction) and cost (height suppression) associated with extended use of medication.ResultsFor ratings of symptom severity, the ADHD-LNCG comparison was statistically significant for the parent/self-report average (0.51±0.04, p&nbsp
- Subjects :
- Persistence (psychology)
Male
Pediatrics
Outcome Assessment
Physiology
medicine.medical_treatment
Attention-deficit
Aftercare
treatment trials
Severity of Illness Index
Attention-deficit/hyperactivity disorder
follow-up studies
growth
longitudinal studies
medication effects
Pediatrics, Perinatology and Child Health
Developmental and Educational Psychology
Psychiatry and Mental Health
law.invention
0302 clinical medicine
Randomized controlled trial
law
Outcome Assessment, Health Care
Outcome assessment (health care)
Psychology
Multimodal treatment
Young adult
MTA Cooperative Group
Child
Pediatric
05 social sciences
Perinatology and Child Health
Combined Modality Therapy
Psychiatry and Mental health
Mental Health
hyperactivity disorder
Cognitive Sciences
Female
Attention deficit disorder
Human
050104 developmental & child psychology
Adult
medicine.medical_specialty
Adolescent
Clinical Trials and Supportive Activities
Clinical Sciences
Developmental & Child Psychology
Pathophysiology
Article
03 medical and health sciences
Young Adult
Clinical Research
Severity of illness
medicine
Attention deficit hyperactivity disorder
Humans
0501 psychology and cognitive sciences
Multimodality cancer therapy
Psychiatry
Follow up
medicine.disease
Attention Deficit Hyperactivity Disorder (ADHD)
Body Height
Brain Disorders
Health Care
Stimulant
Attention Deficit Disorder with Hyperactivity
Observational study
Controlled study
030217 neurology & neurosurgery
Follow-Up Studies
Subjects
Details
- ISSN :
- 14697610
- Volume :
- 58
- Issue :
- 6
- Database :
- OpenAIRE
- Journal :
- Journal of child psychology and psychiatry, and allied disciplines
- Accession number :
- edsair.doi.dedup.....59e63c47d0331e92dca1c0284a1c1786